The dialogue between art and synthetic biology in this work takes place as a simulation in real time of the programming of biological fibers by means of nanomachines.

The reprogramming of these fibers in the real world, using a biochip, could lead to a cure for Alzheimer’s disease, for example.

How would the interaction between these biomachines and human beings be? Would they still be considered machines? Or as biomanufactured beings-objects, entities that dwell in the ontological abyss between the living and the non-living?

Architect and artscience research José Wagner Garcia Research general advisory prof. dr. Glaucius Oliva and prof. dr. Richard Garratt (Instituto de Física de São Carlos) Project conception and development Italo A. Cavini (Instituto de Física de São Carlos) Real-time images Rose Maria Carlos [associate professor with the Chemistry Department at Universidade Federal de São Carlos; Fapesp 2017/00839-1 (USFCar) process] and Mariana Pigozzi Cali (master's degree candidate in inorganic chemistry at the Chemistry Department at USFCar) Experiments conducted at the Photobiophysics Laboratory – prof. Amando Siuiti Ito [Physics Department at Faculdade de Filosofia, Ciências e Letras in Ribeirão Preto, Universidade de São Paulo (FFCLRP/USP)] Neural fuzzy network profa. dra. Sandra Sandri [Instituto Nacional de Pesquisas Espaciais (Inpe)] Evolutionary computation prof. dr. José Carlos Becceneri (Inpe) Biochip Micromanufacturing Aristides Pavani Filho and Maria das Graças de Almeida [Centro de Tecnologia da Informação (CTI)] Installation of S.A.D. Synthetic Alzheimer Disease prof. dr. Luciano Silva [Visual Computational Laboratory (LCV) at Universidade Presbiteriana Mackenzie] Synthetic biology Danilo Zampronio (SynBio USP) Co-author and text revision Rozelia Medeiros Musical composition Wilson Sukorski Graphic computing Fabio Jara Gasparim Interactive didactic project Rita Wu (SynBio USP) Programming, robotics, mockup design, 3D Estevao Trabbold Programming, robotics, game design, 3D James Vitor Lopes Peret Video mapping Alexandre M. Ferraz and VJ Herms